YOGYAKARTA Internal body clocks or known as circadiant rhythms regulate sleep and are maintained by a person in line with changes in the light level. Research found that the rhythm of the body's internal clocks made muscles and tissues functioning properly.

The body's internal clock is affected by day and dark at night. Disorders in the sleep-building cycle can have health consequences, according to research. The sleep-building cycle, influenced by the rhythm of the circadier. If the cycle is disordered, the body in the meetabolism of the food is also erratic. Disorder functions, often experienced by the elderly. Furthermore, according to studies, the circdian cycle that affects the sleep-tagunic cycle is irregular, can be overcome by changing the meal time.

Brain health coach Ryan Glatt, CPT., NBC-HWC., said that the impact of circadiant rhythm has an impact on muscle aging through central and peripheral clock interactions. So it is very important that research uncovers the underlying biological path and its health implications.

The 2nd study, apart from finding a connection between a change in eating time that improves circadian rhythm, found communication between brain clocks and peripheral clocks in the skin. Where epidermis hours correct brain signals to ensure skin cells replicate when the risk of mutation is lowest.

Research published in Science reported by Medical News Today, Wednesday, May 15, researchers used mouse models. The researchers saw patterns of activity inactivity, oxygen consumption, energy disbursement, and glucose oxidation as well as unusual lipids in knockout mice (KOs) compared to wild-type mice. This difference suggests that their circadiant rhythm is disrupted.

We know from other studies that the function of peripheral and central clocks is simultaneously very complex. Two-way communication between central and peripheral networks has been previously reported; but this study shows how peripheral clocks in frame muscles and central clocks signal each other, explained Amy Hutchison, Ph.D., postdoctoral researcher at Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide Medical School, The University of Adelaide, Australia.

Interestingly, this study shows the unique ability of muscle clocks to act as gatekeepers of central clock signals and maintain muscle function and demonstrate the importance of frame muscles as an active network metabolic system. As age grows, the sleep-building cycle changes. Old people lose muscle mass, and these two things are closely related. So based on research, it recommends changing the meal time to improve the circadiant cycle and muscle function.

Although this research still needs to be done on humans and comprehensively, but as input for healthier life. Hutchison, who did not take part in this study, also gave recommendations. That limiting meal times can improve the circadirian system. Eating with time constraints, or intermittent fasting, has proven to have several metabolic benefits, including weight loss and positive effects on non-alcoholic fatty liver disease, cancer, and cardiovascular disease.


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