JAKARTA - Bryan Johnson, a 47-year-old tech entrepreneur known for his efforts to slow aging, has decided to stop consuming rapamycin, a drug that has been used for years to increase his longevity.
Although every morning he takes 54 pills as part of his routine, Bryan found rapamycin may have more bad effects than good.
Johnson is known for following one of the most aggressive rapamycin protocols in the world. Rapamycin is an immunosuppressant drug commonly used by transplant patients to prevent organ rejection.
Although the FDA (US Food and Drug Administration) does not approve rapamycin for anti-aging therapy, some doctors have prescribed it because research on mice shows the drug can prolong healthy age.
However, in a Netflix documentary entitled Don't Die: The Man Who Wants to Live Forever, Johnson revealed that he stopped consuming rapamycin at the end of September after almost five years of using it. He admitted that the side effects were too big compared to the benefits.
"I took this because there are several potential long-lived benefits," Johnson said in the film, quoted from the page The Economic Times.
"This is something that exists in the long-lived community that makes people excited," he continued.
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During the experiment, Johnson tried various doses and schedules for rapamycin consumption, including weekly and weekly doses, to optimize its benefits while minimizing side effects.
"I think a long life, people think it must be a bit crazy. I also take immune-pressure drugs. When I found out about it, people reacted 'It's weird and why did you do that?'," he said.
However, it experiences skin infection and soft tissue, abnormal blood fat levels, increased blood sugar, and a higher rest rate. The dose adjustment didn't help, Bryan decided to stop completely.
Medical experts in the documentary also voice their concerns about the use of rapamycin by humans. Because this drug suppresses the immune system, it risks developing harmful bacterial infections, such as pneumonia or cellulitis.
Johnson spends USD2 million or IDR 32 billion per year on various medical and treatment tests to slow aging. A few months ago, it made a total plasma exchange, where its body fluids were replaced with pure albumin, a protein found in the human blood plasma.
In 2023, he had a blood transfusion with his son who was still a teenager, whom he called a 'blood boy'.
Johnson, who made a fortune after selling the company to eBay, is now fully committed to slowing the aging process with a combination of very strict diet, sleep and exercise.
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