Stages That Occur In The Krebs Cycle In The Body

YOGYAKARTA C Cycle of Krebs is one of the biochemical reactions that can occur in humans. This cycle is also known as the citrate acid cycle, the Tricarboxylic Acid Cycle (TCA) cycle, or the triarboxylate acid cycle. This cycle is important to generate energy. The stages that occur in the krebs cycle start from changing the acetyl-CoA molecule so that it produces ATP, NADH and FADH2. Of the three results, it is then converted back into energy. For more details, see the following article.

As is known, the Krebs Cycle is part of the human body's metabolic process which is closely related to energy. This cycle occurs in cells, precisely in mitochondria, which is often referred to as the "power plant" of cells.

Reporting from the official Microbenotes website, the stages of the Krebs Cycle start from the diffocusing of the acetyl KoA and CO2 pyrocratic molecules. Dikarboksilation is important because it turns pyruvate into an assetl-CoA so it can enter the Krebs Cycle. The following is the stage on the Krebs Cycle to become energy.

Once the acetyl-CoA is generated from the pyruvate decarboxing process joins the oxaloacetate molecule. The incorporation is done to form citrate acid.

After the citric acid is formed, the next stage is decarboxyllation, namely the removal of one carbon atom from the molecule. The sitrat dioxide acid then produces NADH which brings energy in the form of electrons by leaving alpha-ketogluat, a molecule that has five carbon atoms.

Alpha-ketogluat is then decarboxilated again to release CO2. In this process the resulting NADH is more and produces uccinyl-CoA, a new molecule that has four carbon atoms.

The next stage is that the uccinyl-CoA molecule is changed again to succinic acid or succine acid. At this stage the energy is released to form the ATP, namely the body's main energy molecule.

Succinic acid or succinate acid that was successfully formed was then converted into fumarat through dioxide. This process also produces FADH2, other molecules that also carry energy in the form of electrons.

Fumarat was then hydrated to form malat, namely molecules with four carbon atoms. The hydration that occurs is done reversiblely with hydrate fumarat enzymes. This means that the process can occur in two directions, namely that the fumarat can be hydrated into malat, or malat can be converted back into fumarat. This process can be carried out according to conditions in the cells.

In the last stage, malat needs dioxide to produce oxaloacetates, the molecules needed to start the next Krebs Cycle. In this process it produces NADH. This reaction completes the cycle.

Those are the stages that occur in Cycle Krebs. Visit VOI.id to get more interesting information.