Getting To Know The Cytokine Storm That Hit Deddy Corbuzier After Being Declared Negative For COVID-19

Illustration of a human lung mannequin (Unsplash/Robina Weermeijer)

JAKARTA – Almost two weeks after reporting his break from social media, Deddy Corbuzier informed him about his health.

Through the verified Instagram account @mastercorbuzier, he reported that he was positive for COVID-19 and without any symptoms had lung damage.

After a week, reported by VOI yesterday, Sunday, August 22, a cytokine storm hit Deddy Corbuzier even after testing negative for COVID-19. What exactly was the cytokine storm he was experiencing?

Cytokine storm or cytokine storm is an overreaction of the immune system. When the body is exposed to the SARS-CoV-2 virus, white blood cells play a role in fighting foreign infectants. This is an immune system response in which white blood cells produce cytokines.

Cytokines are proteins produced by the immune system. Its function is to provide cell signal markers.

Citing Kompas, Monday, August 23, proteins produced by cytokines move towards infected tissues. In this regard, cell receptors trigger an inflammatory reaction. Normally, cytokines only work briefly and stop when the body's immune response is in the index area.

Mahirsyah Wellyan, Responsible for Logistics and Pharmaceutical Supplies at Dr. Karyadi Hospital, Semarang, explained that in the case of COVID-19, cytokines move to lung tissue to protect against SARS-CoV-2 attacks.

Therefore the lungs can become severely inflamed because the immune system is trying hard to kill the virus. Unfortunately, lung inflammation can continue even after the infection is over. This is as experienced by Deddy Corbuzier, that even after being tested negative for COVID-19, a cytokine storm subverts the body's defenses.

The causes of cytokine storms, described in the journal of the US National Center for Biotechnology Information (NCBI), are pathological features such as acute respiratory distress (ARDS), coagulation, and organ dysfunction.

The severity of illness to death can also be affected by cytokine storms. Even a cytokine storm can cause multiorgan failure throughout the body.

Medical symptoms associated with a cytokine storm include fever, capillary leak syndrome, disseminated intravascular coagulation, acute respiratory distress syndrome, and multiorgan failure.

In certain cases, as experienced by Deddy Corbuzier, initially did not experience any symptoms. Therefore, clinical investigation is important to understand the signal of cytokine storm so that effective treatment strategies can be implemented immediately.

According to Mahirsyah's explanation, the cytokine storm depends on the body's resistance to the incoming virus. If the immune system is strong, the incoming virus can be defeated. Cytokine storm treatment is carried out under clinical trials and medical procedures.