Minister of Health (Menkes) Budi Gunadi Sadikin revealed that there was an bidder for acute kidney failure in a child named Fomepizole.
According to him, Fomepizole is able to reduce the number of cases of kidney failure in children because it can prevent ethylon glycol contamination from becoming toxic acid.
This was conveyed by the Minister of Health during a meeting with Commission IX of the DPR today. The meeting was also attended by the Head of BPOM Penny Lukito, the Head of IDAI Piprim Basarah, the Joint Secretary General of the Pharmaceutical Company Andreas Bayu Aji, and the Executive Director of IPMG Inge Kusuma.
"Fomepizole and ethanol act as competitive inhibitors of glycol ethylene in conjunction with alcohol dehydrogenase enzymes. Fomepizole and ethanol have the ability to bind to 8 thousand times larger Alcohol Dehydrogenase enzymes than glycol ethylene," he said at the Parliament Complex, Senayan, Jakarta, Wednesday, November 2.
"Thus, the intervention of Fomepizole and ethanol is able to prevent the metabolism of glycol ethylene from becoming toxic acid metabolites that can damage the kidneys," continued the Minister of Health.
Budi said that since the temporary ban on the consumption of sirop drugs, cases of acute kidney failure in children have decreased. When the case spreads, the Ministry of Health has also provided Fomepizole as an antidotum for patients.
"So far, the use of Fomepizole has indicated an improvement in the kidney function of GGAPA patients," he said.
On the same occasion, the Minister of Health said that his party had handed over hundreds of medicines to the DKI Jakarta Labkesda and the National Police Laboratory to be tested. In the content of hundreds of drugs, cypress is found in ethylene glycol chemical compounds.
"The results are that most of the chemical ethylene glycol which is a spruce or solvent material commonly used for medicines," he continued.
The Ministry of Health also concluded that the drugs consumed by acute kidney failure patients are likely to be exposed to harmful chemical compounds from taken cirrhop drugs.
The Minister of Health ensures that his party will continue to coordinate with BPOM so that the handling of acute kidney failure in children is continued to completion.
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