Celine Dion Adanya Penyakit Langka Stiff Person Syndrome, Know Causes, Symptoms, And How To Overcome It

Celine Dion (Photo: IG @celinedion)

YOGYAKARTA - A well-known Canadian singer, Celine Dion, has a rare neurological disease called Stiff Person Syndrome (SPS). This news was conveyed directly by Celine Dione through a video uploaded on social media.

Celine shared her health condition that forced her to postpone and cancel a series of concert schedules.

"Recently, I was newly diagnosed with a very rare nerve condition called stiff person syndrome, which affects about one in a million people," Celine said.

Celine Dion's health disorders make her experience muscle seizures that weaken the body.

The Stiff Person Syndrome Foundation calls SPS an attack on the central nervous system, especially the brain and spinal cord. As a result of this syndrome, sufferers can become disabled, depending on a wheelchair or lying in bed, unable to work and take care of themselves.

Cause of Stiff Person Syndrome Adapted by Celine Dion

According to Scott D. Newsome, DO., FAAN., professor of neurology and Director of Stiff Person Syndrome at the Johns Hopkins School of Medicine, the cause of rare neurological disorders such as those experienced by Celine Dione, is not known for sure.

However, the researchers suspect Stiff Person Syndrome may have been caused by autoimmune reactions.

In particular, the immune system appears to be attacking a protein called the decarboxylase of glutamic acid (GAD), and producing a substance called gamma-aminobutirat acid (GABA), according to the Yaleledicine page.

GABA helps regulate motor neurons by reducing their activity. Low GABA levels can cause these neurons to light continuously even when they are not supposed to. About 60-80 percent of people with stiff person syndrome have anti-GAD antibodies in the blood and cerebrospinal fluids.

Many SPS patients also have other autoimmune diseases, such as type 1, vitiligo diabetes, and pernisiosous anemia. SPS also occurs more frequently in people with certain types of cancer, including breast cancer, lung cancer, kidney cancer, thyroid cancer, colon cancer, and lymphoma. However, the reasons for this connection are still unknown.

Symptoms of Stiff Person Syndrome

Still from Yalemedicine, Stiff Person Syndrome's main symptoms are stiff muscles in the body trunk and leg, along with episodes of severe muscle seizures.

These symptoms can be triggered by excitation from outside, such as loud noise and emotional pressure.

The muscle failure experienced by people with SPS can be so severe that it causes the person to fall. The muscles gradually loosened after the excitation disappeared.

These symptoms can cause difficulty walking. People with Stiff Person Syndrome also tend to have symptoms of depression and anxiety. This is partly due to unpredictable diseases. On the other hand, patients also have a lower level of GABA neurotransmitters, which regulate anxiety.

Most people start experiencing symptoms between the ages of 30 and 60.

How to Overcome Stiff Diseases of Person Syndrome

Currently, there is no cure that can treat Stiff Person Syndrome. The treatment given by doctors is only to relieve symptoms.

The drugs that can be used to suppress the symptoms of Stiff Person Syndrome are:

In addition to the three types of drugs above, doctors usually provide intravenous immunuglobulin and plasmaphoresis therapy. Physical therapy and aquatic therapy are also important for people with Stiff Person Syndrome.

That's the information about the causes, symptoms, and how to deal with Stiff Person Syndrome. Hopefully it will be useful!